Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Microbiology
Buyer’s remorse: how OAS1 genetic variants acquired by modern humans make them vulnerable to severe COVID-19
After almost 2.5 years of the COVID-19 pandemic, we are still trying to understand the factors contributing to differences in disease severity and who should be treated with what, when, and why. Our paper addresses some of these questions from genetic, molecular, evolutionary, and clinical angles.
Understanding pathoadaptation of the periodontal microbiome
It is now becoming critical to understand how a synergistic community of virulent bacteria can persist below the gum line, modulate inflammatory responses, and promote gum infections and inflammation, with strong implications in several systemic diseases in adults.
Emu: a novel computational tool for more precise community profiles from full-length 16S sequences
Emu is a novel software designed to establish microbial community profiles with full-length 16S rRNA gene sequences from error-prone nanopore devices.
Exploring donor difference in neonatal fecal microbiota transplantation
Using a controlled preterm piglet model, we found rectal fecal microbiota transplantation manifested clinically and microbiologically in a donor-dependent manner. Metagenomic analysis revealed strain-level phylogenetic separation of the engrafted lactobacilli strains according to the donors.
