Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Protocols & Methods
Super-resolution volume imaging realized by scanning single molecule localization microscopy (scanSMLM)
Scanning SMLM is probably the simplest, hassle-free, easy-to-use, economical, and most reliable technique for upgrading an existing SMLM to a 3D volume super-resolution system.
SnapFISH: a computational pipeline to identify chromatin loops from multiplexed DNA FISH data
Multiplexed DNA fluorescence in situ hybridization (FISH) imaging technology has been developed to map the folding of chromatin fibers at tens of nanometers and several kilobases in resolution in single cells. We present SnapFISH to process the multiplexed DNA FISH data and identify chromatin loops.
New insight into the onset, progression, and treatment of eosinophilic esophagitis (EoE)
We provided adequate data to support the crucial role of IL-18 in the development of EoE and showed the pretreatment with NLRP3 and caspase-1 inhibitors such as MCC950, BHB, and VX-765 protects against both food allergen- and aeroallergen-induced EoE pathogenesis in an EoE experimental model.
