Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
New tools to study human oral microbiome in vitro
Our oral tissue model represents a breakthrough in the field of oral tissue engineering, as it allows to investigate in a tractable, yet relevant, in vitro model the mechanisms and biomarkers that could result in disruption of oral tissue homeostasis.
MicroRNA dynamics, PTEN/PI3K/AKT signaling, and their relationship to breast cancer: prospects for pharmaceuticals and natural product application
Breast Cancer, PI3K/PTEN/AKT signaling pathway, microRNAs, Natural Products, Potential drugs.
Stable isotope evidence for pre-colonial maize agriculture and animal management in the Bolivian Amazon
Biochemical analysis of the bone collagen of humans and muscovy ducks reveals the significance of maize to diets at the same time as significant socioeconomic complexity.
Can Nanomagnetic-Based Cementitious Material Seal Cracked Rocks?
Due to limited resistance to dispersion and inadequate bonding properties exhibited by traditional grouts (cementitious materials), we developed a new material to fill cracks in rocks and improve its bonding strength.
A Treasure Hunt in Chemistry: AI Leading the Way to New Materials
Chemistry is a treasure hunt, with countless “treasures” hidden in element combinations. AI is transforming material discovery. Our research uses simple oxides to predict complex compositions, revealing hidden patterns and paving the way for groundbreaking discoveries.
Structure of human mitochondrial Mg2+ channel Mrs2
Mrs2 is a mitochondrial Mg2+ channel that is essential for metabolic function. We determined cryo-EM structures of human Mrs2 under different conditions, revealing a novel molecular mechanism of Mg2+ permeation through Mrs2.
Structure of human ZAC channel
ZAC is a Zn2+ and H⁺-activated cation channel and a critical target for neuropsychiatric drugs. we report the structures of human ZAC, providing insights into the gating and activation mechanisms of ZAC.
Surviving a Pandemic Without a Local Health Department
We found that counties in Pennsylvania without a local health department had poorer health outcomes compared to counties with a local health department. Policy changes are needed in Pennsylvania to establish and maintain a local health department in every community.
