Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
AF1q is a universal marker of neuroblastoma that sustains N-Myc expression and drives tumorigenesis
AF1Q is an oncogene with roles in leukemia and solid tumor progression. Despite its expression in neural tissues, no role for AF1Q in tumors of neural origin has been reported. We found AF1Q is a universal marker of neuroblastoma that is essential for neuroblastoma cell survival and tumorigenicity.
Inflammation-suppressing cornea-in-a-syringe with anti-viral GF19 peptide promotes regeneration in HSV-1 infected rabbit corneas
Here, we present a behind-the-science snapshot of our multinational EuroNanoMed III project. We are researchers and clinicians from the Maisonneuve-Rosemont Hospital Research Centre and Université de Montréal, Quebec (Canada), Vilnius University, Lithuania, and University of Cordoba, Spain.
Behind FISHnCHIPs
FISHnCHIPs simultaneously targets co-expressed gene groups, boosting signals 2-20 fold over single-gene methods. This enhanced sensitivity allows rapid, sensitive, and robust whole-tissue profiling under low magnification, and applicable for analyses of clinical tissue samples with low RNA quality.
In situ observation of ligand-induced electrocatalytic microenvironment formation at the nanometer scale
We probed a bias-induced ligand-assisted formation of an electrochemical microenvironment at the nanometer scale using in situ nano-FTIR and Raman spectroscopies.
