Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
This study identified 43 novel non-HLA loci associated with Type 1 diabetes (T1D) in patients harboring low GRS.
Models underestimate aerosol acidity throughout the atmosphere
Acidity is an important aerosol property, as it impacts numerous physicochemical properties. However, models either neglect to include aerosol acidity, or have not been robustly tested for various environments. We show that the atmosphere is generally acidic, and models miss this important feature.
Structure-function analysis of a new type of endoperoxidase
Endoperoxidase NvfI catalyzes the incorporation of “three” oxygen atoms, including an endoperoxide and a hydroxyl group, into its substrate asnovolin A, in a single enzyme turnover reaction through a different mechanism from those of previously characterized endoperoxidases.
