Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Quantitating Enzyme Activity in Organelles
A novel DNA-based probe technology for the quantification of enzyme activity in vivo
Harnessing insights from one child case of post-treatment control of HIV
Individuals who have the ability to control HIV-1 to undetectable levels either naturally in the absence of antiretroviral treatment (ART) (elite controllers), or those who achieve this after starting ART early in infection and later stopping ART (post-treatment controllers) – tell us that HIV remission is possible. This study describes virological and immunological features associated with a single case of durable post-treatment control of HIV-1 in a young South African child.
A Mom's Motivation to Monitor Breathing
My team at UC Irvine has developed small Band-Aid© like sensors that can continuously monitor both respiration rate and volume. We made these disposable sensors with an inexpensive children’s toy, Shrinky-Dinks.
Link to paper: DOI: 10.1038/s41746-019-0083-3
Digital health devices: More choice does not necessarily mean better choices
We have seen many examples of digital health innovation failing to gain traction in the real world setting. Often is it because the sensor or app at the heart of it all just wasn't right for the job. Could we approach this in a better way, such that we can enhance the chances of success?