Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Rein in or Ruin: Ubiquitylation of CDC42 Ensures Membrane Homeostasis and Regulates Brain Development
The small Rho GTPase CDC42 drives actin polymerization and membrane protrusion. Unchecked cytoskeletal remodeling can push tumor cells toward EMT or even cell death. Thus, elucidating how cells both activate and quench CDC42 signaling to maintain membrane homeostasis has been a central question.
Breaking the Silence: Ethnic Inequalities in Cancer Pain Relief in the UK
Our study, published in the British Journal of Cancer, reveals patients with cancer from minority ethnic backgrounds in England are prescribed fewer opioids for pain relief at the end of life and require more emergency department visits, highlighting urgent inequalities in palliative care
Inflation, food insecurity, and mental health: Generation Z’s burden in emerging Europe
Inflation is more than rising prices. For Gen Z in emerging Europe, it means food insecurity, financial stress, and worsening mental health. Our study reveals how economic hardship reshapes student well-being.
Understanding Wing Dams and Their Role in Flood Risk
Wing dams improve navigation, but their impact on water levels and flood risk has long been debated. By combining detailed 3D and large-scale 1D models, we uncover how different riverbed types shape long-term water level responses to these structures.
Human Activities and Climate Disturbances Are Accelerating the Release of the World’s Largest Ocean Mercury Sink
First quantification of the continental shelf’s capacity to sequester the toxic heavy metal mercury reveals it stores six times more than previously known, but human activities and climate disturbances may reverse its role into a source of marine pollution
