Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Bioengineering & Biotechnology
Aptamer array precisely assembled on DNA origami for potent and reversible anticoagulation in hemodialysis
A structurally well-defined platform is described here to organize thrombin-binding aptamers, enabling the synergistic effects of thrombin recognition and anticoagulation.
A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function
AKA: A method to make T-cells better tumor killers
A five-transgene cassette confers broad-spectrum resistance to a fungal rust pathogen in wheat
Engineering durable disease resistance in crop plants
A multi-center study benchmarking single-cell RNA sequencing technologies using reference samples
Charles Wang, Wanqiu Chen and Malcolm Moos
The birth of the T7-DIVA system for continuous evolution of proteins
In recent years there has been a growing interest for the development of molecular evolution techniques. We describe the birth of T7-DIVA system, an in vivo mutagenesis system for the fast directed evolution of proteins in a continuous manner and with minimal manipulation.
In-vivo efficacy of biodegradable ultrahigh ductility Mg-Li-Zn alloy tracheal stents for pediatric airway obstruction
Tracheal stenosis, a debilitating condition limits air passage to lungs affecting pediatric and adult populations. Current biodegradable polymeric stent therapies are far from ideal. An ultrahigh ductility biodegradable magnesium based alloy (LZ61-KBMS) developed herein may offer a viable solution.
High-Throughput Preparation of Radioprotective Polymers via Hantzsch’s Reaction for In Vivo X-ray Damage Determination
Story behind this article (Nat. Commun. 10.1038/s41467-020-20027-0): how did this project come about and some of the research results.
