Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Biomedical Research
Did Domestication Reshape the Aging Brain? What Dogs—and Wolves—May Reveal About Alzheimer’s Vulnerability
Did domestication reshape brain aging? Comparing domestic dogs and gray wolves, we found that neurodegeneration-associated risk factors were more pronounced in dogs, suggesting that domestication and modern environments may have shifted vulnerability to cognitive decline.
Single cell snapshot analyses under proper representation reveal that epithelial-mesenchymal transition couples at G1 and G2/M
Numerous computational approaches have been developed to infer cell state transition trajectories from snapshot single-cell data. With the fast-accumulating computational methods that have been developed, several fundamental issues have been rarely investigated, which is the focus of this study.
From Refusal to Recovery: What One Family Taught Us About Health Literacy in TB
One patient’s refusal to take TB medicine despite counselling exposed a deeper issue: a gap in health literacy. Our study investigates how this gap impacts patients especially those with comorbidities and what it means for TB elimination in India.
Why do males and females sometimes differ in recognizing others?
Identity recognition are dynamically shaped by the emotional valence of social experiences.
Secondary data use of tocilizumab clinical studies to address regulatory needs for rare and pediatric trials
As part of the European INVENTS research project (Innovative designs, extrapolation, simulation methods and evidence-tools for rare and pediatric diseases), a study involving the use of secondary data from 10,000 patients in 20 clinical studies has been registered in the ISRCTN registry.
Comparison of transient elastography and shear wave elastography as a routine diagnostic method for assessing liver fibrosis in Indian participants with liver steatosis
Liver health is one of the biggest health challenges in India. Millions of people—often without any symptoms—have fatty liver disease. While fatty liver itself may sound harmless, it can gradually progress to liver scarring (fibrosis), liver failure, or even liver cancer if not detected in time.