Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Microbiology
Body weight index indicates the responses of the fecal microbiota, metabolome and proteome to beef/chicken-based diet alterations in Chinese volunteers
This work highlighted the role of BMI as an important factor predicting changes in gut homeostasis in response to meat consumption. Compared with the chicken-based diet, the beef-based diet may induce more allergic and inflammation-related responses in high- and middle- BMI Chinese.
Staying alive: sinking Trichodesmium fixes nitrogen in the dark ocean
Sunlight extinguishes about 150 m in the ocean, retaining photosynthetic microbes such as the diazotrophic cyanobacteria in the surface ocean layer. Here we find that Trichodesmium, a key photosynthetic diazotroph, fixes nitrogen while sinking into the deep ocean down to 1000 m depth.
Buyer’s remorse: how OAS1 genetic variants acquired by modern humans make them vulnerable to severe COVID-19
After almost 2.5 years of the COVID-19 pandemic, we are still trying to understand the factors contributing to differences in disease severity and who should be treated with what, when, and why. Our paper addresses some of these questions from genetic, molecular, evolutionary, and clinical angles.
Understanding pathoadaptation of the periodontal microbiome
It is now becoming critical to understand how a synergistic community of virulent bacteria can persist below the gum line, modulate inflammatory responses, and promote gum infections and inflammation, with strong implications in several systemic diseases in adults.
Emu: a novel computational tool for more precise community profiles from full-length 16S sequences
Emu is a novel software designed to establish microbial community profiles with full-length 16S rRNA gene sequences from error-prone nanopore devices.