Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Neuroscience
Why rats (and humans) addicted to alcohol may not respond to psilocybin treatment
In our paper, we show how severity of alcohol relapse in rats can affect psilocybin’s mode of action
Rescuing retromer in Parkinson's disease
Both Vp35 p.D620N and LRRK2 pathogenic variants cause late-onset, familial Parkinson's disease. In vivo, we show Vps35 p.D620N activates LRRK2 kinase activity, impairs the recycling and physiologic function of the dopamine transporter (DAT), and can be rescued by LRRK2 kinase inhibitors.
Digital Haptics for Navigating without Vision
How could we learn and navigate through spaces without using vision? Digital haptic technologies may be an alternative and new technologies are making this a reality.
Wake slow waves in focal human epilepsy impact network activity and cognition
During sleep, slow waves carry a restorative function in normalizing neuronal excitability. Here, using intracranial recordings from patients with focal epilepsy, we provide evidence of a beneficial impact of wake slow waves against excitability associated with epileptiform discharges.
