Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Identification of leukemia-initiating cells by transcriptome profiling in a mouse model
Transcriptome profiling and identification of leukemia-initiating cells in a mouse model expressing the fusion gene CBFB-MYH11, which results from chromosome 16 inversion, a common chromosome abnormality in human acute myeloid leukemia.
Designing next-generation norepinephrine indicators for in vivo imaging
We engineered a novel family of genetically-encoded fluorescent norepinephrine indicators in green and red. These indicators exhibit exceptional sensitivity, ligand-specificity, and temporal resolution, surpassing prior indicators and enabling the detection of norepinephrine in living animals.
