Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Growers: Hard to kill
Last year, tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) killed 1.5 million people, overtaking HIV/ AIDS – this reflects massive advances in treatment of HIV, which haven’t been matched in the treatment of TB. Although almost all cases of TB are curable, the treatment is extremely long, and no progress has been made in shortening treatment in 40 years, since the introduction of the drug rifampicin: which reduced the regimen duration from 18 to 6 months.
Artificial Intelligence in Colonoscopy
In our Nature Biomedical Engineering paper, we developed a deep learning algorithm for the detection of polyps in colonoscopy images and videos, and validated it with a large-scale collection of newly acquired data. The new technology could help to improve adenoma detection rate during colonoscopy.
Fun-sized Fungal Genomics: Expanding biological knowledge with single cells
Bridging the knowledge gap between the described and estimated total fungal species is accompanied by new challenges and will require new techniques. Single-cell genomics can help.