Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Voting right does not equal voting against climate action; yet, it is often interpreted and used in that way.
Where climate action is more needed than ever, politicians who want to reduce climate action are being elected, with Trump being the most recent example. Consequently, it is often assumed that people care little about climate change. But is this assumption correct?
Navigating New Territory in a Small Lab
The journey behind our recent paper was a long one, filled with hurdles and unexpected turns that we learned to navigate along the way. Working from a small lab with limited resources, we embarked on a project that introduced us to the complex and evolving field of biomolecular phase separation.
Mevalonate pathway inhibition reduces bladder cancer metastasis by modulating RhoB protein stability and integrin β1 localization
Activating the mevalonate (MVA) pathway increases bladder cancer (BLCA) spread. High MVA enzyme levels predict worse outcomes. Drugs like zoledronic acid or simvastatin blocking this pathway reduce cancer cell migration by affecting the protein RhoB. Targeting the MVA pathway could help treat BLCA.
VEXAS Syndrome: Hope, Challenges, Solutions, and the Road Ahead
This post aims to raise awareness, build understanding, and inspire action within the medical and patient communities alike. The road is long, but with continued collaboration and innovation, we can offer new hope to those affected by VEXAS syndrome.
