Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
A Retrospective Analysis of Biliary Tract Cancer Patients Presented to the Molecular Tumor Board at the Comprehensive Cancer Center Munich
With the rising importance of precision oncology in biliary tract cancer (BTC), this analysis describes the clinical and molecular characteristics of this patients.
A generative model of memory construction and consolidation
A computational model shows how the hippocampus encodes episodic memories and replays them to train generative neocortical models of the world, so that conceptual and sensory representations of experience can be recombined for imagination and memory.
Getting to 1.5C might need some course adjustments
This blog reports the thinking behind a study undertaken by a team of researchers across Imperial College London and the Met Office Hadley Centre, to look at how climate change mitigation pathways could be adjusted as future information is received, around both climate and technological conditions.
Unveiling the Journey Behind a Breakthrough in Early Detection of Pancreatic Cancer
New paper demonstrates effectiveness of exosome isolation technology in detecting Stage I and II pancreatic ductal adenocarcinoma (PDAC)
How we respond to stressors
Behind the Paper: Risk for diagnosis or treatment of mood or anxiety disorders in adults after SARS-CoV-2 infection, 2020–2022 https://doi.org/10.1038/s41380-024-02414-x
Exploring the advanced material cultures 45,000 years ago in East Asia
An international team has reported Initial Upper Palaeolithic archaeological remains dating to 45,000 years ago from the Shiyu site in northern China. Shiyu is the oldest and easternmost site of its kind. The discovery reshapes our understanding of the timing and routes of human migration in Asia.
A potential patient stratification biomarker for Parkinson's disease based on LRRK2-mediated cellular alterations in peripheral blood
A recent study substantiates a role for increased LRRK2 kinase activity in some idiopathic Parkinson's disease patients and suggests that blood-based patient stratification approaches hold promise in nominating patients who may benefit from LRRK2-related therapeutics.