Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
How to make CRISPR arrays (and what we learned in the process)
CRISPR arrays have proven difficult to generate due to the repetitive nature of their repeats. We developed a new method for assembly CRISPR arrays called CRATES, and we gained unique insights into CRISPR RNA biogenesis along the way.
Cancer-associated secondary lymphoedema
Ensuring healthy lives and promoting the well-being at all ages is the aim of Sustainable Development Goal #3. Dr Stanley Rockson discusses secondary lymphoedema in individuals who have or survived cancer, and how developments in basic and clinical research can help address the global targets.
The SMOG 2 software package - a versatile tool to simulate complex biomolecular assemblies
We present the SMOG 2 package, which is a handy and practical tool to help with MD simulations of biomolecules. It provides a flexible interface that can adapt to a wide variety of scientific needs. Here, we provide an overview of the protocol as well as several implementation tips and examples.
