Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Behind the Paper: A Bioinspired Journey to Needle-Free Drug Delivery
This blog post offers a glimpse into the research journey that led to our recent publication in Nature detailing microjet delivery (MiDe) systems for gastrointestinal drug delivery.
Human HDAC6 senses valine abundancy to regulate DNA damage
Valine specifically binds to the primate-specific SE14 repeat domain of HDAC6, retaining it in the cytoplasm. Valine deprivation triggers HDAC6 nuclear shift, increasing DNA demethylation and damage via TET2 activation. Valine restriction inhibits tumor growth, and enhances the effects of PARPis.
Does fire limit tropical tree cover?
What happens when we remove fire from the tropics? Our study reveals the surprising impact fire has on tropical tree cover—and why it’s more complex than we thought.
Unveiling the Secrets of Longevity in India
Mapmygenome's pioneering longevity study on Indians living over 85 reveals fascinating genetic secrets. Discoveries include variants linked to slower heart rate, short height, disease protection, and the FOX03A gene, offering valuable insights into longevity within the Indian population.
Tailored pore-confined single-site iron(III) catalyst for selective CH4 oxidation to CH3OH or CH3CO2H using O2
The direct conversion of methane into methanol and acetic acid offers a sustainable pathway for producing high-value chemicals. We achieve this transformation by harnessing a multifunctional iron(III) dihydroxyl catalytic species within a MOF framework, using molecular oxygen as the oxidant.
Does the Use of Mobile Phone Affect Male Fertility?
The rapid advancement and ubiquitous adoption of mobile phones, laptops, and wireless technologies such as Wi-Fi and 5G have undeniably transformed our daily lives and communication methods.
Real-world outcomes following biochemical recurrence after definitive therapy with a short prostate-specific antigen doubling time: potential role of early secondary treatment
Real-world evidence suggests a potential role of early secondary treatment in prostate cancer with biochemical recurrence after primary therapy.
Reduced aerosol transport from South Asia to the Tibetan Plateau following the January 2021 sudden stratospheric warming event
This study, for the first time, examined the impact of the sudden stratospheric warming in January 2021 on the transboundary transport of aerosols from South Asia to the TP from the stratospheric dimension.