Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Stromal signal promotes Chromatin Remodeling and BET inhibitor Resistance in Cancer cells
BRD4 has a pro-tumorigenic role but non-cell-autonomous mechanisms of BRD4 activation need to be elucidated. Here the authors unravel a mechanism by which CAFs activate BRD4 and induce resistance to BET inhibitors in cancer cells through IL6/IL8 signaling.
The New Platforms of Health Care
For the past century, the dominant locations for assessing health and delivering health care have been clinics and hospitals. That is about to change.
Next generation sequencer repurposed for the oligonucleotide libraries purification
We recently developed oligonucleotide libraries purification technology called "MOPSS". We repurposed next generation sequencing (NGS) instrument for massively parallel purification of oligonucleotides libraries and we believe that MOPSS will flourish nucleic acid-based technologies.
