Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Microbiology
Pathogenic bacteria hijack probiotic signal to activate virulence factor production and promote its survival
Are probiotics effective in preventing infections? what is their efficacy in physiologically relevant settings? We explored the beneficial effects of a human probiotic against a human pathogen in infection-relevant environments and discovered few unexpected but translationally relevant findings.
Bridging the gap: immunobridging large-scale efficacy data of a tetravalent dengue vaccine (TAK-003) from children and teenagers to adults
Behind the Paper : LeFevre, I., et al. Bridging the immunogenicity of a tetravalent dengue vaccine (TAK-003) from children and adolescents to adults. NPJ Vaccines 8, 75 (2023).
Microbial co-occurrences on catheters from long-term catheterized patients
This study determines the positive and negative microbial co-occurrences between uropathogenic species in the lower urinary tract microenvironment of long-term catheterized patients.
Using degenerating genes to understand the evolution of rare intact genes across bacteria
An overview and broader look at the paper "Pseudogenes act as a neutral reference for detecting selection in prokaryotic pangenomes" published in Nature Ecology & Evolution (2024).
Blog post authors: Gavin M. Douglas and B. Jesse Shapiro
Creating the next generation of protein sequence reference libraries for marine microbial eukaryotes
The Marine Functional Eukaryotic Reference Taxa (MarFERReT) project is an up-to-date protein sequence reference library designed for flexible and adaptive use and re-use in marine microbial eukaryotic research.
