Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
A compendium of 32,277 metagenome-assembled genomes and over 80 million genes from the early-life human gut microbiome
Given the specificity of early-life human gut microbiome regarding the microbial composition and functions, building a set of high-quality reference genomes from early life is desirable for a good microbial characterization, and discovering interactions between early-life gut microbiome and health.
Sticklebacks and Hopeless Monsters
What types of genes and mutations underlie the striking anatomical differences found in wild species? New genetic research shows that wild stickleback fish evolve major changes in their defensive armor using the vertebrate homologs of the famous Hox genes of Drosophila. Four-winged fruit flies have been described as "hopeless monsters" that would never survive outside the laboratory. However, sticklebacks with different bony spine patterns are thriving under a full range of fitness constraints in natural environments, providing a striking example of how wild vertebrate species evolve new body structures through repeated regulatory mutations in key developmental control genes.
Everything Everywhere All at Once
how multi-substrate screening can lead to the discovery of general catalysts
Seasonal Prediction of Severity Index of Harmful Algal Blooms in Lake Erie using Machine Learning
Mukul Tewari, IBM Thomas J. Watson Research Center, Yorktown Heights, NY, USA