Behind the Paper

The real stories behind the latest research papers, from conception to publication, the highs and the lows

Sorting Nexin 3 (SNX3), a member of the recycling retromer complex, is a critical player in the epidermal growth factor (EGF) stimulated EGFR network in triple-negative breast cancers.

Elif Erson-Bensan, PhD

Nov 08, 2021

Oncogene

Behind the Paper

ERK signal inhibits lung cancer

Lung cancer is the #1 cancer killer in the U.S. Lung cancer’s heterogenous pathology and complicated oncogenic signaling networks have impeded care.

Michelle Mendoza

Nov 08, 2021

Profiling immune functions to advance malaria vaccines

Behind the Paper

Profiling immune functions to advance malaria vaccines

James Beeson

Nov 07, 2021

Rejuvenation of tumour-specific T cells through bispecific antibodies targeting PD-L1 on dendritic cells

Nature Biomedical Engineering

Behind the Paper

Rejuvenation of tumour-specific T cells through bispecific antibodies targeting PD-L1 on dendritic cells

Longchao Liu and 1 other

Nov 06, 2021

British Journal of Cancer

Behind the Paper

Higher Bleeding Rates Found with Direct Oral Anticoagulants in Myeloproliferative Neoplasm Patients

In this study we evaluated thrombosis and bleeding outcomes in myeloproliferative neoplasm (MPN) patients treated with direct oral anticoagulants (DOACs). We found an unexpected high cumulative incidence of bleeding, emphasizing the need for continued rigorous evaluation of DOACs in MPNs.

Joan How

Nov 05, 2021

Varied Responses to Temperature Amongst the Oceans' Smallest Plants

Nature Communications

Behind the Paper

Varied Responses to Temperature Amongst the Oceans' Smallest Plants

Stephanie Anderson

Nov 05, 2021

The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis

Leukemia

Behind the Paper

The tumor suppressor MIR139 is silenced by POLR2M to promote AML oncogenesis

C.J. Stavast and 1 other

Nov 05, 2021

Following 10 years of forest growth shows the value of functional diversity

Nature Ecology & Evolution

Behind the Paper

Following 10 years of forest growth shows the value of functional diversity

Xiaojuan Liu and 1 other

Nov 05, 2021

Nature Communications

Behind the Paper

N1-methyladenosinemethylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism

Zusen Fan and 1 other

Nov 04, 2021

Efficient and Stable Perovskite Solar Cells and Modules using Tailored Organic Halide Passivators

Nature Communications

Behind the Paper

Efficient and Stable Perovskite Solar Cells and Modules using Tailored Organic Halide Passivators

Cheng Liu

Nov 04, 2021

Nature Astronomy

Behind the Paper

Detection of fluorine in absorption in a star-forming galaxy at redshift 4.4

Fluorine is a fascinating element in many ways. We report the detection of fluorine (in the form of hydrogen fluoride) in a lensed galaxy at z=4.4, seen as it was 1.3 billion years after the Big Bang. This detection may give valuable clues to the highly debated formation conditions of this element.

Maximilien Franco

Nov 04, 2021

Tau pathology: Piecing the Puzzle together

Communications Biology

Behind the Paper

Tau pathology: Piecing the Puzzle together

Emily Hill

Nov 04, 2021

How microbes deal with the complex soil geometry?

Communications Biology

Behind the Paper

How microbes deal with the complex soil geometry?

Carlos Arellano-Caicedo

Nov 04, 2021

Tracing Native Mexican adaptive evolution history

Behind the Paper

Tracing Native Mexican adaptive evolution history

Claudia Ojeda-Granados

Nov 04, 2021

Nature Communications

Behind the Paper

Challenge-oriented design of nanoagent enabling dual-mitochondrial-damage synergistic antitumor therapy

We developed a new type of MOFs-based core-shell nanoagents that enables near infrared (NIR) light-triggered two distinct antitumor mechanisms, namely oxidative stress and calcium overload, with both of them contributing to the mitochondria-dysfunction-associated eradication of tumor cells.

Zhiyuan Tian

Nov 04, 2021

Coprecipitation experiments between carboxylic acids and ferrihydrite give new insights into organic carbon preservation in natural environments.

Communications Earth & Environment

Behind the Paper

Coprecipitation experiments between carboxylic acids and ferrihydrite give new insights into organic carbon preservation in natural environments.

Lisa Curti

Nov 04, 2021

New method to learn motor skills

npj Science of Learning

Behind the Paper

New method to learn motor skills

Taewon Kim

Nov 04, 2021

Nature Astronomy

Behind the Paper

Massive Galaxies May be Crucial for the Enrichment of Cosmic Metal in the Early Universe

We report a galaxy around a strong metal absorber at redshift of 6. This galaxy has halo mass of four hundred billion solar mass, an order of magnitude more massive than that expected from simulations, suggesting that massive galaxies are important in transporting metals than perviously thought.

Zheng Cai

Nov 04, 2021

Non-CAMonical photosynthesis in an aquatic lycophyte

Nature Communications

Behind the Paper

Non-CAMonical photosynthesis in an aquatic lycophyte

David Wickell

Nov 03, 2021

No evidence school closures reduce the spread of COVID-19

Nature Medicine

Behind the Paper

No evidence school closures reduce the spread of COVID-19

Charles McClean and 2 others

Nov 03, 2021

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