Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Structure of human mGlu3-arrestin complex
In this paper, we reported the structures of two mGlu3-βarr1 complex with 2:1 and 2:2 stoichiometries. The mGlu3 in an inactive conformation engages βarr1 through phosphorylated C-terminal tail and intracellular loops.
PGRMC2: The discovery of pressure-volume regulator
Using different techniques, our study suggests the important role of PGRMC2 as a pressure-volume regulator in the heart.