Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Carbenoid-involved Reactions Integrated with Scaffold-based Screening Generates a Nav1.7 inhibitor
The synthetic accessible virtual inventory (SAVI) has attracted attention due to its compound synthesis accessibility and structural diversity. The carbenoid-involved reactions (CIR) are suitable for enumerating SAVI.
Recycling of silicon solar panels through a salt-etching approach
We report a simple salt-etching approach to recycle Ag and Si from end-of-life Si solar panels without using toxic mineral acids and generating secondary
pollution.
'SIMONA' software package released!
The software package SIMONA (an acronym standing for SIgned MOdels for Network Analysis) is designed to solve maximum-entropy models for signed networks and generate the related ensembles.
Do Large Language Models reason like us?
We show Large Language Models (LLMs) have become capable of incredible feats of reasoning, previously reserved to humans. Regardless, we bring forth evidence that LLM and human reasoning are not the same, as they respond differently to strategic cues, and are ruled by different biases.
New tricks from old drugs: repurposing the 80s
A paper in Molecular Psychiatry describes a new cell biological mechanism regulated by antidepressants, showing how a single dose of a drug fluvoxamine may open up the brain for drug delivery. Can this finding signal the beginning of a brand new career for the 30+ year-old drugs?
Spatial Proteomics Offer Novel Insights into Rare Lymphomas with Sparse Tumor B-Cells
In Younes S et al. Blood Cancer J. 2024 [https://doi.org/10.1038/s41408-024-01073-z], we explore the cellular composition and spatial organization of two rare and related lymphomas, NLPHL and THRLBCL, to gain insight into their biological behavior.
Artificial Intelligence (AI): A Potential Game Changer in Regenerative Orthopedics—A Scoping Review
Regenerative orthopedics is a field of medicine that focuses on helping the body heal itself from orthopedic injuries and ailments.
These approaches hold great promise for treating conditions that were previously difficult to manage.
