Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
CPSF4 regulates circRNA formation and microRNA mediated gene silencing in hepatocellular carcinoma
In our study in Oncogene, we demonstrate that CPSF4 acts as an oncogene in HCC through circRNA inhibition and disruption of miRNA-mediated gene silencing.
CAR-T Cell Therapy: Current Limitations and Potential Strategies
Chimeric antigen receptor (CAR)-T cell therapy is a new treatment option for certain cancers whose use in clinical practice presents novel challenges and opportunities. Here we highlight a review outlining some limitations and potential strategies to overcome the limitations of CAR-T cell therapy.
Complete shut-down
How SARS-CoV-2 shuts down host gene expression and takes over the cellular translation machinery.
Antibody cocktail immunotherapy against cancer
Fan Yang, & Yi Fan
Department of Radiation Oncology, University of Pennsylvania Perelman School of Medicine,
Philadelphia, Pennsylvania, USA 19104
Visualizing oxygen redox and unlocking electric aviation
The serendipitous journey behind understanding the inner workings of Li-rich cathodes and how that can provide a way to satisfy the "AND problem" for battery cathodes.
