Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Balance is key: Deep lung microbial dynamics and host-microbe interactions.
Lower respiratory tract harbour characteristic microbial communities. We explored the deep lung microbiota dynamics of the transplanted lung over time. Our study shows that a predominant "balanced" microbiota resembling that of a healthy lung is key for clinical stability and immune homeostasis.
Bacterial promoters - a new direction
Bacterial promoters have always been considered to be directional, only recruiting RNAP in one orientation. In our paper, we show that promoters are frequently able to recruit polymerase in both orientations, resulting in divergent transcription. We call these bidirectional promoters.
Artificial Intelligence, Cancer, and Azithromycin
The explosion of available data and revolution in algorithms have created a moment with infinite potential.
Decrypting the code of chromosome 1q abnormalities in multiple myeloma
One of the most common cytogenetic abnormalities in myeloma is one of the most widely debated and poorly understood. We have summarized the literature of this mysterious genomic aberration and call for standardization as a key to understanding the significance of +1q and improving patient outcomes.
