Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: General & Internal Medicine
People Aren’t Stupid: They’re Wary of False Information About COVID-19
Here is a brief overview of the article, which highlights that social media does not exert a negative influence on COVID-19 vaccination.
Decoding the Hidden Microbiome Behind Triple-Negative Breast Cancer
Our study provides the first comprehensive meta-analysis of the breast tissue microbiome in triple-negative breast cancer. By uncovering distinct microbial players, we highlight how these microbes may fuel cancer aggressiveness and open the door to microbiome-based therapies
Association between sickle cell disease and autoimmune diseases in Saudi population
Although previous studies in the Saudi population have examined a number of autoimmune diseases, no study in the Kingdom of Saudi Arabia has examined the coexistence of sickle cell disease and autoimmune diseases.
Cholesterol Shapes How the Brain’s Neurotransmitter Transporter for Serotonin Works
New research shows that membrane cholesterol fine-tunes serotonin, dopamine, and norepinephrine transporters—affecting neurotransmitter recycling, drug responses, and potentially brain disorders.
Reducing Unreasonable Lab Requests with Demand Management Tools
This quality improvement project was implemented to reduce unnecessary laboratory testing requests with a focus on chromogenic and coagulation tests to improve efficiency and productivity in the hematology department of a hospital in Saudi Arabia.
Hidden fat in children’s muscles: what it reveals about their cardiometabolic health
Obesity is often defined as abnormal or excessive fat accumulation, usually measured by the BMI. However, BMI does not tell us the whole story. Not all fat in the body behaves in the same way, and where fat is stored might make a big difference for our health.
Alcohol Blocks Gut Immune Gatekeepers, Compromising Defense Against Bacteria in ALD
mAChR4 -regulated goblet cell–associated antigen passages (GAPs) train gut immune cells, acting as sentinels, maintaining antimicrobial defense in the gut-liver axis, and positioning mAChR4 agonism and GAP formation as a therapeutic checkpoint for alcohol-associated liver disease (ALD).
Unanswered Questions: AML with IDH Mutations
The optimal induction regimen for intensive chemotherapy-eligible patients with IDH-mutated AML has not been established. In our recently published study, we report outcomes of newly diagnosed IDH-mutated AML treated with intensive chemotherapy plus venetoclax, highlighting efficacy and challenges.
