Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Impact of residential solid fuel usage and fuel conversion on children’s lung function
Solid fuel combustion exposure is a leading global health risk factor, yet evidence on its effects, especially on vulnerable children, is sparse. Our study highlights the adverse impact of solid fuel usage on children and the need to promote clean fuel usage for this vulnerable population.
Burned Area Increasingly Explained by Climate Change
Climate change is increasingly recognized as a key driver of wildfire activity. But the seemingly simple question, "How much has climate change altered burned area?" has not been answered before. Here, we provide a first quantification of this.
COVID-19's Hidden Toll: Analyzing Changes in Marriage, Divorce, and Birth Rates
Our recent study examines the significant demographic changes in Kerman Province, Iran, during the COVID-19 pandemic, focusing on marriage, divorce, birth, and death rates. Utilizing Poisson regression and interrupted time-series models, we analyzed data spanning from 2017 to 2020.
Time is Precious
Our laboratory has been studying the long noncoding RNA ( lncRNA ) termed FIRRE for over 15 years and yet we have only recently realized we missed something critical: TIME. Time is precious and has changed the way we think about the entire field !
Pectolinarigenin inhibits bladder urothelial carcinoma cell proliferation by regulating DNA damage/autophagy pathways
Pectolinarigenin (PEC) from herbal medicine targets DNA topoisomerase II alpha (TOP2A) in bladder cancer (BLCA), causing DNA damage and blocking cell division. It inhibits autophagy, boosting its effectiveness. Combined with gemcitabine, PEC more effectively halts BLCA growth.
Melatonin inhibits bladder tumorigenesis by suppressing PPARγ/ENO1-mediated glycolysis
Melatonin may help fight bladder cancer (BLCA) by slowing cancer cell energy production and increasing chemotherapy effectiveness, by targeting ENO1 to enhance gemcitabine’s impact and involving reactive oxygen species and PPARγ regulation. This suggests new methods for improving BLCA treatment.
