Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
27.09% Efficiency Silicon Heterojunction Back Contact Solar Cell and Going Beyond
a new generation of heterojunction back contact (HBC) solar cells that not only push efficiency boundaries but also address key challenges in design and implementation.
The Critical Role of Cell Types in Alzheimer’s Disease
Alzheimer’s disease (AD) is widely known for its characteristic features, such as amyloid plaques and neurofibrillary tangles, but the role of different brain cell types in the progression of the disease is becoming increasingly important in research.
The promise in the Sound of a Cough
The image of a world where doctors can diagnose diseases like tuberculosis (TB) simply by listening to the sound of your cough might sound like something from science fiction. Yet, thanks to advances in artificial intelligence (AI) and machine learning, this future is closer than ever before.
Conditional reprogramming: Modeling urological cancer and translation to clinics
Patient-derived conditional reprogramming (CR) lets cells grow indefinitely, aiding in studying cancer, developing treatments, and advancing personalized medicine. This approach shows promise for improving urological cancer treatment.
Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway
Simvastatin, a drug for heart disease by lowering cholesterol, also slows bladder cancer (BLCA) growth. It stops BLCA cells from multiplying by activating PPARγ, a fatty aicd/lipid metabolism pathway. This effect can be reversed with PPARγ inhibitors.
MYBL2 promotes proliferation and metastasis of bladder cancer through transactivation of CDCA3
Our research reveals that MYBL2, a gene-regulating protein, is elevated in bladder cancer (BLCA) and linked to worse patient outcomes. It boosts BLCA growth and spread by activating the CDCA3 gene, working with FOXM1 to enhance cancer traits. This identifies MYBL2 as a key promoter of BLCA.
Two Nobel Prizes in Medicine gained thanks to a worm
One year has gone by since the achievement of the Nobel Prize in Physiology or Medicine by Katalin Karikó and Drew Weissman for the development and subsequent improvement of the messenger RNA (mRNA) technology.
Non-invasive diagnosis and surveillance of bladder cancer with driver and passenger DNAmethylation in a prospective cohort study
We studied DNA methylation markers in urine to enhance bladder cancer detection and classification. Our findings could transform non-invasive diagnosis and monitoring of this cancer and potentially other types as well, leading to major advances in cancer management with less invasive techniques.
Decoding sex-specific metabolomic biomarkers in the loggerhead sea turtle (Caretta caretta)
Is there a distinct metabolomic profile between male and female loggerhead turtles? Are there useful biomarkers for sex classification in this species?
