Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Secondary versus de novo ontogeny for AML in the era of molecular genetics
AML has long been classified and prognosticated based on ontogeny, that is, whether it is de novo or secondary. But several reports have suggested that disease genetics drive these outcomes as opposed to ontogeny. Here, we examine this relationship in greater detail.
Detecting changes and loss of smell during COVID-19 with Large Language Models
Reports in March 2020 suggested new loss of smell as one of the symptoms of COVID-19. We here implemented a method that could use a straightforward collection of written comments describing changes in smell perception to reveal characteristics and predict who was infected by the SARS-CoV-2 virus
New insight into the onset, progression, and treatment of eosinophilic esophagitis (EoE)
We provided adequate data to support the crucial role of IL-18 in the development of EoE and showed the pretreatment with NLRP3 and caspase-1 inhibitors such as MCC950, BHB, and VX-765 protects against both food allergen- and aeroallergen-induced EoE pathogenesis in an EoE experimental model.
