Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
It is time for a global ban of declaw in cats
I graduated as a veterinarian in Lyon, France, in 1992 — the very year the European Union banned declawing cats. When I later arrived in North America to specialize in anesthesia and pain management, I was shocked to see how common this procedure still was. I had never even learned how to do it.
Alcohol Blocks Gut Immune Gatekeepers, Compromising Defense Against Bacteria in ALD
mAChR4 -regulated goblet cell–associated antigen passages (GAPs) train gut immune cells, acting as sentinels, maintaining antimicrobial defense in the gut-liver axis, and positioning mAChR4 agonism and GAP formation as a therapeutic checkpoint for alcohol-associated liver disease (ALD).
RNA structure beyond canonical base pairs guided by evolution
This is a novel method that integrates the prediction of RNA secondary structure with that of RNA 3D motifs. RNA 3D motifs steer the assembly of canonical helices into a 3D structure. Fully integrated prediction of 3D motifs together with base pairs is a vital step toward inferring RNA 3D structure.
People overlook subtractive solutions to mental health problems
Across eight studies, we explored the tendency that people (and AI) have to give people advice about their mental health that involves telling them to do more.
Behind the Paper: Introducing Computational Prophylaxis and the COHRCIE Framework
I discovered a gap in anchoring my PhD research as a field. I defined its role and established a framework to guide implementations. This led to two contributions: Computational Prophylaxis (a new term) and the COHRCIE Framework: Computational One Health Research Compliance and Integrated Ethics.
