Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Thyroid hormone receptor β is a newly identified transcription factor to suppress cancer stem cell activity
Cancer stem cells (CSCs) enable adaptive plasticity in tumors that contributes to therapy resistance and poor disease outcomes. Here, we show that thyroid hormone receptor β (TRβ) suppresses CSCs through the transcriptional regulation of CSC-related genes, thereby impeding tumorigenesis.
Behind the Book | The evolution of quantum optics
My new textbook illustrates how quantum optics has come to play an enabling role in many areas of modern science
Cryo-EM Structure of Lipopolysaccharide Transporter LptDE Opens the Door to Antibiotics Design
Bacteria display very different biochemistry from human cells, which can be exploited for designing new antibiotics with less side-effects. Detailed insights into the architecture and function of LptDE transporter complexes has been made possible by new Cryo-EM structures.
Risk of winterization cost explains unpreparedness of Texan power system during winter storm Uri
In shock we witnessed the reports about the catastrophic failure of the Texan power system in February 2021. Although based in Europe, we started immediately analyzing why Texan energy-only markets have not given the right incentives to prepare the infrastructure against such rare extreme events.