Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Machine-learning design of ductile 2-GPa Alloys
Machine learning enabled the design of 2 GPa ductile alloys with truly uniform elongation. A unique microstructure promotes high work hardening and ductility, overcoming century-long challenges and key limitations of existing ultra-strong alloys.
A PurFect strategy for tuberculosis drug discovery?
Tuberculosis treatment urgently needs new drugs targeting novel pathways. Here, we present a new compound which inhibits PurF, a key enzyme in purine biosynthesis. These findings offer a promising strategy to tackle drug-resistant TB and enhance the effectiveness of current treatment regimens.
From Mutation to Peptide: Resolving Proteome Complexity with moPepGen
A graph-based algorithm to detect variant peptides from the proteome—fast, flexible, and biologically faithful.
