Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Bioengineering & Biotechnology
Volumetric imaging with uniform 3D resolution across scales
Light-sheet fluorescence microscopy (LSFM) enables gentle and efficient volumetric imaging. Through axially swept light-sheet microscopy (ASLM), the resolution in the third dimension can be made equal to the lateral resolution, simplifying viewing and analysis of three-dimensional samples.
De novo-designed light-activated Reaction Centers pave the way toward new photosynthetic pathways
Proteins designed from scratch reproduce the multi-step electron transfer cascade that leads to charge separation in photosynthesis.
Graph deep learning detects contextual prognostic biomarkers from whole slide images
We recently developed a graph deep learning method that considers contextual histopathological features from the whole-slide images. We show that the proposed method can provide interpretable prognostic biomarkers in a semi-supervised manner. We believe it will aid prognostic tasks in the future.
Multiplexed Electrochemical detects both Nucleic acids and Proteins
In this paper, we designed an electrochemical diagnostic device that bridges biology and electronics to simultaneously detect viral RNA and human antibodies for diagnosing and tracking the course of COVID-19 and potentially other infections.
CRISPR Off-Targets: One SNP can make all the difference
In a recent paper, we used ultra-deep sequencing to determine whether CRISPR was introducing or enriching for mutations in cancer genes.
