Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Biomedical Research
Unlocking a Detrimental Role of IGF1 in Osteoarthritis: A New Target for Therapeutic Intervention?
Osteoarthritis is a common joint disease that leads to pain, stiffness and limited mobility, for which no effective treatments are available. My team and I, driven by the desire to address this medical need, studied the biology of cartilage and this led us to uncover a surprising player in OA: IGF1.
The detection, biological function, and liquid biopsy application of extracellular vesicle-associated DNA
This review summarizes and discusses advances in EV-associated DNA (EV-DNA) research, with an emphasis on EV-DNA detection at the population-EV and single-EV levels, gene transfer-associated biological functions, and clinical applications as biomarkers for disease liquid biopsy.