Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Cell & Molecular Biology
Pathogenic bacteria hijack probiotic signal to activate virulence factor production and promote its survival
Are probiotics effective in preventing infections? what is their efficacy in physiologically relevant settings? We explored the beneficial effects of a human probiotic against a human pathogen in infection-relevant environments and discovered few unexpected but translationally relevant findings.
USP43 stabilizes c-Myc to promote glycolysis and metastasis in bladder cancer
This study identified USP43 as a deubiquitinase which regulates glycolytic metabolism and c-Myc transcriptional activity and revealed a USP43/c-Myc positive feedback loop that contributes to the progression of BLCA.
The first alumminum ion receptor in living organisms
How living organisms perceive and transduce signals is a fundamental question in life sciences. Particularly, the ability to sense and discriminatively respond to nutrient and toxic ions is crucial for survival of all organisms, which is especially true for non-motile plants.
