Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Automated Differentiation of Wide QRS Complex Tachycardia: A Game-Changer in Cardiac Care
Wide QRS complex tachycardia (WCT) is a critical arrhythmia requiring accurate differentiation into ventricular tachycardia (VT) or supraventricular wide complex tachycardia (SWCT). Our machine learning-based algorithms use novel ECG features to enhance diagnostic precision, speed, and reliability.
Towards Sustainable Benchmarking in AI for Digital Pathology
Deep Learning (DL) can transform medical diagnostics, but its environmental cost is often overlooked. A new benchmarking approach for DL in pathology is vital, integrating carbon footprint with diagnostic performance to develop sustainable, efficient AI solutions.
Intrapartum Ultrasound Video Analysis
Ultrasound Video Segmentation of Pubic Symphysis and Fetal Head for Angle of Progression Measurement
Offsetting Ozempic's Price Tag with Lower Food Costs
Many are rightfully concerned with the prices of novel anti-obesity medications, which can limit access to these transformational drugs. However, many U.S. patients reported spending less on food , with savings offsetting out of pocket medication costs for 41% of the surveyed sample.
T cells in amyotrophic lateral sclerosis
The immune system’s role in amyotrophic lateral sclerosis (ALS) progression is increasingly recognized, but the impact of peripheral immune cells remains unclear. Using single-cell RNA sequencing, we analyzed blood immune cells to explore their link to disease progression in ALS patients.
Plasminogen activator inhibitor-2 and impaired fibrinolysis in pregnancy and sickle cell anemia
This is the first study that aimed to determine antigen levels in plasma and genotypes of PAI-2 in pregnant and non-pregnant homozygous sickle cell anemia (SCA) patients.
Heavy metal contamination in urban roadside vegetables: origins, exposure pathways, and health implications
Did you know vegetables grown along urban highways can accumulate heavy metals like lead and cadmium from vehicle emissions? My latest review article dives into the alarming health risks and solutions to this hidden issue.
Concurrent DNA hypomethylation and epigenomic reprogramming driven by androgen receptor binding in bladder cancer oncogenesis
CUT&Tag sequencing reveals how the androgen receptor (AR) drives tumor heterogeneity and gender disparities in bladder cancer through epigenetic reprogramming.
Genome organization around inter-chromosomal transcription hubs
The genome architecture is a critical element in transcriptional regulation. Our study reveals an intricate network of interactions between related genomic loci, even in the absence of direct regulatory mechanisms, and provides new perspectives on the evolutionary significance of these interactions.
Evolution of fast-growing piscivorous herring in the young Baltic Sea
In this blog I explain my long-standing interest in herring genetics and why we failed to detect any population structure in this species with a handful of neutral markers more than 40 years ago as well as the background for our recent surprising discovery of piscivorous herring in the Baltic Sea.
