Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Precise recognition of benzonitrile derivatives with supramolecular macrocycle of phosphorylated cavitand by co-crystallization method
While establishing specific lock-and-key recognition for structure-based drug design is typically based on the computational method, co-crystallization could mimic molecular docking. Herein, we report a supramolecular macrocycle that can precisely recognize benzonitrile derivatives.
Quantifying Cell-State Densities in Single-Cell Phenotypic Landscapes Using Mellon
What constitutes a tissue based on single-cell data and how can we represent it computationally? This question led us to develop Mellon, a tool to quantify cell-state densities and reveal dynamics of cell-differentiation processes. Here's a behind-the-scenes look at our journey.
5G WDM-based bidirectional OWC system with signal remodulation employing cascaded RSOAs
A 5G WDM-based bidirectional OWC system with cascaded RSOAs to effectively remove the downstream data is demonstrated. The uplink performance is greatly enhanced by using two RSOAs to remove the downstream data. This demonstrated system holds great potential to enhance 5G advanced communications.
Changes in the seasonality and regionality of tornadoes in the United States
The occurrence of U.S. tornadoes, and tornado outbreaks, have exhibited significant changes both temporally and spatially.
Distal Femoral Non-union: Moving Forward with a Systematic Approach
This systematic review sheds fresh light on the challenging realm of distal femoral non-union management. Distal femur fractures are common, and non-union presents a significant hurdle for patients and surgeons alike. https://link.springer.com/article/10.1007/s43465-024-01205-4
1 in 5 Salmonella Typhi bacteria are Vi capsule variants: insights for future studies on the capsule variants of S. Typhi
This study presents a noteworthy discovery: Salmonella Vi capsule variants can arise from a single point mutation
