Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Biomedical Research
A potential patient stratification biomarker for Parkinson's disease based on LRRK2-mediated cellular alterations in peripheral blood
A recent study substantiates a role for increased LRRK2 kinase activity in some idiopathic Parkinson's disease patients and suggests that blood-based patient stratification approaches hold promise in nominating patients who may benefit from LRRK2-related therapeutics.
A call for individual risk stratification on early morbidity and mortality in patients with newly diagnosed multiple myeloma
Behind the paper of „Predictors of early morbidity and mortality in newly diagnosed multiple myeloma: data from five randomized, controlled, phase III trials in 3700 patients” - an international team effort from the HOVON, EMN and GMMG study groups.
Computational pathology identifies immune-mediated collagen disruption to predict clinical outcomes in gynecologic malignancies
A computational pathology tool to quantitatively characterize the immune-collagen relationship in gynecologic cancers. It enables prognostic stratification of patients and provides insights into the biology of the tumor microenvironment.
DeepRTAlign: toward accurate retention time alignment for large cohort mass spectrometry data analysis
Retention time (RT) alignment is a crucial step in large cohort proteomics and metabolomics studies. Here, the authors introduce DeepRTAlign, a deep learning tool for RT alignment that shows high identification sensitivity and quantitative accuracy.
