Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Biomedical Research
Common Conditions of use Elements – Deceptively simple use conditions.
This blog describes the ideas and work behind the publication: Common conditions of use elements. Atomic concepts for consistent and effective information governance .
Effectiveness of DialBetesPlus, a self-management support system for diabetic kidney disease: Randomized controlled trial
We conducted a large RCT of the DialBetesPlus mHealth intervention. In this trial, we applied the intervention to patients in Japan with diabetic kidney disease. DialBetesPlus seeks to change patient behavior by helping them meet the lifestyle guidelines given to them by their physicians.
Diet switch pre-vaccination improves immune response and metabolic status in formerly obese mice
Metabolic disease is linked to severe complications upon influenza virus infection, making a vaccination a priority. Yet, vaccine responses are less effective in these same hosts. Here we examined how the timing of diet switching affected influenza vaccine efficacy in diet-induced obese mice.
Clinical Testing of the cAd3-Ebola and MVA-EbolaZ vaccines
In two parallel phase I/Ib trials, both cAd3-vectored Ebola and MVA-EbolaZ vaccines were safe and well tolerated in healthy adults recruited from the United States and Uganda. The vaccines were immunogenic and elicited durable antibody responses.
Quantifying how Single Dose Ad26.COV2.S Vaccine Efficacy Depends on Spike Sequence Features
The phase 3 ENSEMBLE trial of a single dose of Janssen’s Ad26.COV2.S vaccine showed an overall vaccine efficacy of 56% against symptomatic COVID-19. Looking at the Spike sequences of infecting viruses reveals a more complex picture.
