Epichaperomics: Illuminating the Secrets of Protein Interactions in Disease Research
Introducing Epichaperomics: an emerging omics platform for research to illuminate the secrets of diseases. By studying protein interactions in cells and tissues, it offers valuable insights into disease mechanisms and paves the way for personalized therapies.
Unveiling the Role of Protein Glycosylation: Insights into Conformational Dynamics and Disease Mechanisms
Glycosylation plays a critical role in controlling normal cell functions as well as disease-related conditions. Understanding how sugar modifications impact proteins, including their conformations and interactions, is crucial for unraveling the causes of diseases and developing targeted treatments.
Introducing epiLiver: A High-throughput Test for Early Detection of Hepatocellular Carcinoma
HKG Epitherapeutics and icddr,b present epiLiver, a novel DNA methylation-based test poised to transform early detection of hepatocellular carcinoma (HCC). This innovative test offers a new hope in improving survival rates for those affected by this prevalent cancer.
Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche
Our study sought to identify key elements of the tumor microenvironment (TME) that drive distinct tumor states by defining the spatial organization of the TME. We find the proliferative neighborhood matures TREM2+ immunosuppressive myeloid cells into a self-propagating tumor-immune niche.
