Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Microbiology
Diet switch pre-vaccination improves immune response and metabolic status in formerly obese mice
Metabolic disease is linked to severe complications upon influenza virus infection, making a vaccination a priority. Yet, vaccine responses are less effective in these same hosts. Here we examined how the timing of diet switching affected influenza vaccine efficacy in diet-induced obese mice.
Genomic insights into antibiotic resistance in E. coli ST131 bacteraemia cases in Wales
Our study illuminates the complex genomic landscape of Escherichia coli sequence type (ST)131, a well-known multidrug-resistant clone linked to bloodstream infections in Wales.
Clinical Testing of the cAd3-Ebola and MVA-EbolaZ vaccines
In two parallel phase I/Ib trials, both cAd3-vectored Ebola and MVA-EbolaZ vaccines were safe and well tolerated in healthy adults recruited from the United States and Uganda. The vaccines were immunogenic and elicited durable antibody responses.