Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Neuroscience
Rethinking Brain Sugar — How Glycogen Shapes Tauopathy and Neuroprotection
Alzheimer’s disease is characterized by the buildup of toxic proteins, and lifestyle factors such as diet may influence the risk of developing the condition.
Intracranial recordings from the human brain
Intracranial recordings from epilepsy patients performing memory tasks reveal brain activity from single neurons to system-level dynamics. Our multilingual, multiscale and multimodal BIDS-formatted dataset enables studies of memory, cognition, and brain-computer interfaces across cultural contexts.
Uncovering the Untold Story of the Gut Microbiome in Parkinson’s Disease
The gut microbiome affects our health, including in Parkinson’s disease. While the gut-brain axis and microbial translocation have been suggested, identifying specific bacteria has been challenging. Our meta-analysis of over 1,000 samples aimed to uncover these hidden players: https://rdcu.be/epiUV
Confugenics - the East Asian Iteration of Consumer Eugenics Spells Demographic Disaster
A new terminology - “Confugenics” is thus proposed to describe the prospective intersection of such emerging human enhancement and reprogenetic technologies with the fixation on academic achievements and social status shaped by hyper-competitive social norms within East Asian societies.
Cracking the Genetic Code of Glioblastoma: The Hidden Role of HOX Genes
What if the same genes that shaped us during early development were also driving one of the most lethal brain cancers?
Behind the Paper: Potent antagonist for the MAS-related G protein-coupled receptor and its mouse ortholog with anti-inflammatory, anti- asthmatic, and anti-anaphylactic efficacy in human mast cells and mice
This is the story behind the paper by Al Hamwi et al., recently published in Signal. Transduct. Target. Ther. 2025, 10, 128. doi: 10.1038/s41392-025-02209-8.
How M2 neurons represent locomotion in different environmental contexts
We imaged neuronal activity in the secondary motor cortex using a miniscope while mice moved freely in three distinct environments, and found both context-dependent and context-independent encoding patterns.