Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Biomedical Research
How gut bacteria team up to heal the gut – a story of two papers
Shu Jeffrey Zhu and his team have published two companion papers in Nature Communications: one on the IPA‑PPARα‑HMGCS2‑BHB axis (https://doi.org/10.1038/s41467-026-69341-z) and one on the BC‑ILA‑IPA‑HOPX⁺ reserve stem cell axis (https://doi.org/10.1038/s41467-026-70062-6).
Beyond sperm: how fathers communicate circadian stress to the next generation
For decades, the developmental origins of health and disease framework has been dominated by the maternal environment. Yet, emerging evidence suggests that fathers, even before conception, can shape offspring physiology.
2-DG reprograms mitochondrial metabolism to rescue CD8 T cells impaired by HIV-1
Antiretroviral therapy (ART) effectively suppresses HIV replication but fails to eradicate HIV reservoirs or fully restore immune function in HIV-infected people. In this study, we sought to define how persistent IFN signaling impairs, and how to rescue, CD8⁺ T cells during HIV infection.
Fracture Resistance of Endodontically Treated Premolar Teeth Restored with PEEK Post and Biological Dentin Post: An In Vitro Comparative Study
Polyetheretherketone has a lower Young’s modulus (3–4 GPa)compared to dentin, and it can serve as a shock absorber, lowering the strains placed on the restoration and teeth. For the restoration of teeth that have had endodontic treatment, PEEK posts-and-cores may be a practical substitute.
