Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Biomedical Research
A wireless and bioresorbable approach to temporary pain control
Postoperative pain is often managed with drugs despite clear limitations. We developed a soft wireless and bioresorbable nerve block that uses ultrasound activated triboelectric polymers to control pain signals temporarily and reversibly without electrodes wires or batteries.
Behind the Paper: How PRICKLE3 Found Its Place in WNT/PCP Signalling
Behind every research paper, there is a long story that is usually invisible to the reader. Our paper is no exception. What began as a focused cell biology project gradually developed into a broad, collaborative effort across laboratories, model systems, and countries.
Biology’s snowflakes: why fractal patterns in human kidney cells matter
What do human kidney cells and snowflakes have in common and why does it matter? In a recent Nature Communications paper, we show that fractality is not just descriptive, but a powerful design principle that guides cell maturation, enabling more faithful modelling of complex organs like the kidney.
Reprogramming the morphology of colorectal cancer cells in 3D cultures to enhance therapeutic response
By pairing 3D culture with high-throughput screening, our Communications Biology study reveals how architecture shapes signaling and drug sensitivity – offering insights that could transform treatment strategies for colorectal cancer.
Cardiac lymphatics in Heart Failure
Molecular profiling of cardiac lymphatics in health and disease reveals potential new targets to improve lymphatic drainage in the heart
Hydrogel–elastomer-based conductive nanomembranes for soft bioelectronics
With a total thickness of 350 nm, THIN remains structurally hard and self-supportive, yet upon hydration immediately self-adapts to microscopic topologies and directly integrates with living organisms, thereby bypassing the limitations of previous approaches.
Post-approval safety studies: why they matter
Intravitreal therapies are invaluable for treating diabetic macular oedema (DMO). Often clinical trials do not provide sufficiently large patient populations to assess specific safety concerns, hence the need for post-authorisation safety studies, as shown with long-acting corticosteroids.
