Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Biomedical Research
Clinical Testing of the cAd3-Ebola and MVA-EbolaZ vaccines
In two parallel phase I/Ib trials, both cAd3-vectored Ebola and MVA-EbolaZ vaccines were safe and well tolerated in healthy adults recruited from the United States and Uganda. The vaccines were immunogenic and elicited durable antibody responses.
Quantifying how Single Dose Ad26.COV2.S Vaccine Efficacy Depends on Spike Sequence Features
The phase 3 ENSEMBLE trial of a single dose of Janssen’s Ad26.COV2.S vaccine showed an overall vaccine efficacy of 56% against symptomatic COVID-19. Looking at the Spike sequences of infecting viruses reveals a more complex picture.
Uncovering the intracellular target of candidalysin
Candidalysin, a cytolytic peptide toxin secreted by the human fungal pathogen Candida albicans, is critical for fungal pathogenesis. Yet, its intracellular targets have not been extensively mapped.
Uniting academics and industry to address unmet medical needs
SPARK at Stanford offers a unique model to advance and de-risk therapeutic research in academia
Decoding Radiation-Induced Fibrosis: a computational approach to understanding the damage pathway
Computational modeling of radiation-induced lung fibrosis via the agent-based paradigm provides valuable insights into the initiation and progression of toxicity.
