Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
B Cells: At the intersection of enhanced responses to immunotherapy treatments
B cells have strong clinical significance as drivers of antitumor immunity in triple negative breast cancer. While B cells are known to enhance T cell-mediated tumor killing, we have also uncovered a potential regulatory function, in which they suppress myeloid-derived suppressor cells.
Predicting hospitalization costs via clinical notes
Hospitals only know how much a patient costs once they’ve gone home, making it difficult to plan spending efficiently, but predictive algorithms could help estimate costs early for inpatients.
Genetic architecture of type 1 diabetes with low genetic risk score informed by 41 unreported loci
This study identified 43 novel non-HLA loci associated with Type 1 diabetes (T1D) in patients harboring low GRS.
Models underestimate aerosol acidity throughout the atmosphere
Acidity is an important aerosol property, as it impacts numerous physicochemical properties. However, models either neglect to include aerosol acidity, or have not been robustly tested for various environments. We show that the atmosphere is generally acidic, and models miss this important feature.
