Behind the Paper

The real stories behind the latest research papers, from conception to publication, the highs and the lows

Filtered by: Biomedical Research
Molecular Psychiatry
Behind the Paper

Behind the paper: ADNP is essential for sex-dependent hippocampal neurogenesis, through male unfolded protein response and female mitochondrial gene regulation

Surprisingly, dramatically different molecular pathways regulate adult neurogenesis in males and females. Importantly, these pathways are strongly impacted by the major autism/intellectual disability gene, ADNP and corrected by the ADNP neuroprotective site, the investigational drug davunetide.
Go to the profile of Illana Gozes
Illana Gozes
Dec 24, 2024
Scientific Reports
Behind the Paper

Proteomic analysis of the combined effects of cannabigerol and 3-O-ethyl ascorbic acid on kinase-dependent signalling in UVB-irradiated human keratinocytes

Phytocannabinoid CBG together with EAA, a stable, lipophilic derivative of the vitamin C, recovered human skin cells irradiated by UV light. Their effects on kinases were manifested even after 24 hours. Effects of CBG and EAA were linked to reduced modification of keratinocyte proteins by 4-HNE.
Go to the profile of Neven Žarković +2
Neven Žarković and 2 others
Nov 27, 2024

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