Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Depressive Symptoms among Veterans After COVID-19
A deeper dive into the motivation behind our paper in JGIM titled, "Impact of SARS-CoV-2 Infection on Long-Term Depression Symptoms among Veterans"
Behind the paper: Mantle cell lymphoma is more dynamic than we thought
Mantle cell lymphoma is often viewed as biologically stable over time. By following patients longitudinally with whole-exome sequencing, we found that the disease evolves more than expected, with treatment shaping the accumulation of genetic alterations.
Where Can Hyperscale Data Centers Still Be Built in the United States?
The rapid expansion of hyperscale data centers is straining power systems, land, and climate-sensitive infrastructure. Where can additional capacity still be built under present-day physical and infrastructural constraints? In this piece, I quantified that using large-scale geospatial data.
Single cell snapshot analyses under proper representation reveal that epithelial-mesenchymal transition couples at G1 and G2/M
Numerous computational approaches have been developed to infer cell state transition trajectories from snapshot single-cell data. With the fast-accumulating computational methods that have been developed, several fundamental issues have been rarely investigated, which is the focus of this study.
Visualizing phenotypic heterogeneity in C. difficile gene expression in situ during infection
What happens when you can see bacterial gene expression in situ inside an infected host? By developing fluorescent reporters, we visualized Clostridioides difficile toxin gene expression, revealing unexpected biology that only emerges in the bacterium’s native context of infection.
When Missing Data Can Change the Story
This paper was born from a simple question that kept coming back during our own work on ionospheric trends: how much do data gaps really matter?
Scaffolding the Scaffolder: How Artificial inteligence Can Support Parents Without Replacing Them
When people hear about AIs and children, they imagine robots teaching, chatbots tutoring, or systems that try to replace human instruction. Our research began in a much more ordinary place, yet extraordinary for early development: a caregiver sitting with a child, reading a picture book together.
