Electrochemical CO2 Reduction to Methane by Triazole Molecules
Electrochemical conversion of CO2 into fuels and chemicals with high selectivity and activity is crucial. Our recent work highlights a promising method for CO2-to-CH4 with considerable selectivity and industrially relevant activity by triazole molecules in the presence of trace metal impurities.
Preliminary Phase 2a Readout for a Novel Drug Discovered and Designed Using Generative AI Sets a Major Milestone in AI-Powered Drug Discovery
Insilico Medicine’s AI-Designed Small Molecule Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis Yields Positive, Promising Phase 2 Trial Data
Enabling transport and metabolism in synthetic cells
Decarboxylation of L-malate coupled to L-malate/L-lactate exchange provides metabolic energy for the uptake and metabolism of nutrients in cell-like lipid vesicles.
Antibodies need teamwork!
We develop a novel approach to identify anti-bacterial antibodies from human B cells and reveal that some antibodies can act synergistically
The missing intermediate to form ethanol from carbon dioxide
So far ethanol and ethylene have been suggested as twin products during CO2 electroreduction on copper. Here, via in situ surface-enhanced Raman spectroscopy and density functional theory, we report a specific intermediate for ethanol production, proposing an update reaction mechanism.
Photoreactive fragment pharmacophores explore potential binding sites and provide hits for highly challenging drug targets
Photoaffinity-tagged fragments are increasingly used for convenient hit detection and binding site mapping in early drug discovery. We tackled two important challenges by maximizing the pharmacophore diversity of the core fragments, and by enhancing the labelling efficiency of the photoaffinity tag.
A singular plasmonic-thermoelectric hollow nanostructure inducing apoptosis and cuproptosis for catalytic cancer therapy
A high-performance plasmonic-thermoelectric catalytic therapy utilizing copper vacancy-enriched Cu2−xSe hollow nanospheres. The accumulations of reactive oxygen species, heat and copper ions within cancer cells trigger cuproptosis and apoptosis, creating a synergistic therapeutic effect.
Aggregation-induced electrosynthesis
Aggregation-Induced C-C Bond Formation on an Electrode Driven by the Surface Tension of Water
