Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Biomedical Research
Computational mining the anticancer potential of non-oncology drugs
By building a machine learning model to combining knowledge of cancer genetics and network biology, we developed a personalized method to recommend FDA approved non-oncology drugs for cancer treatment.
Unravelling the Gut Microbiome: Insights from the AWI-Gen 2 Microbiome Project in Africa
Representation in microbiome research is crucial for the effective and broad application of research findings. This relatively large study provides valuable insights into the microbiomes of a diverse population of African women and is conducted within a collaborative, community-engaged framework.
Effect of Stress Management Based Self-Care Counseling on Glycemic Control in Women with Gestational Diabetes Mellitus: A Randomized Controlled Trial Study
Gestational diabetes has become a significant public health concern. According to statistics, this type of diabetes can lead to serious complications for both the mother and the newborn. Therefore, researchers are seeking solutions to help these women and improve their health.
High-valence bismuth(V) nanoplatform to potentiating tumor immunotherapy
A high-valence bismuth(V) nanoplatform has been proposed for the first time for triggering cancer cell death and anti-tumor immune responses via an exogenous excitation-free and endogenous H2O2- and O2-independent reactive oxygen species generation behavior.
Isoxazole-based molecules restore NK cell immune surveillance in hepatocarcinogenesis by targeting TM4SF5 and SLAMF7 linkage
This study has recently been accepted in Signal Transduction and Targeted Therapy. The study reveals a new immune checkpoint of NK cells functional in the livers, a TM4SF5 and SLAMF7 linkage, and TM4SF5-specific isoxazole-based small molecules inhibitory against the linkage.
Understanding the Role of Protein Palmitoylation in Sperm Motility
This research is the first to detail the in situ locations and dynamic changes of protein palmitoylation in sperm, elucidating its crucial role in sperm motility and potential mechanisms involved. The findings suggest possible applications for addressing male infertility.
